Bloodlines
Article Abstract:
The growth of blood vessels around tumour tissue is studied. It is observed that cells nearest to areas of low oxygen (hypoxia) in a tumour are in most need of blood vessels, have the highest expression of vascular endothelial growth factor (VEGF) and hypoxia could directly induce expression of VEGF in cells, thus proving the validation of the hypothesis that targeting the tumour vasculature is viable strategy to treat cancer.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
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Ion implicated in blood pact
Article Abstract:
The implications of nitrite serving as a backup source of nitric oxide to buffer tissue against severe hypoxia are presented. The function of nitrite in vasodilation in response to oxygen levels and oxidative stress in the tissue environment is analyzed.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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Learning to take a deep breath-with BDNF
Article Abstract:
BDNF and serotonin may become important therapeutic targets.Short bursts of hypoxia induce a form of learning in the neuronal network that controls breathing. This process now is shown to share mechanism with synaptic plasticity in the hippocampus.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
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