Clearing the way to mechanisms of autoimmunity
Article Abstract:
The authors discuss the deficits in the apoptotic thymocyte clearance and the increased anti-DNA autoantibody titers discovered in the mice with the Mer tyrosine kinase mutations. These findings made the authors suggest that the impairments in the apoptotic cell clearance could underlie systematic autoimmunity.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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In vivo optical mapping of epileptic foci and surround inhibition in ferret cerebral cortex
Article Abstract:
Research has been conducted on the techniques used to localize epileptiform events in vivo. Results demonstrate that the optical imaging based on intrinsic signals is an excellent method of mapping such epileptiform events such as interictal spikes, ictal onsets and ictal spread in vivo.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Advances in schizophrenia
Article Abstract:
The purpose of this review is to look into the etiology of schizophrenia. The authors came to the conclusion that due to the complex nature of schizophrenia it would take time to completely understand the disease pathogenesis and develop effective therapeutics.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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- Abstracts: Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
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