Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin

Article Abstract:

It can take a long time for the hepatitis C virus to severely damage the liver. In Feb, 1994, batches of anti-D immune globulin used in Ireland in 1977 and 1978 were found to be contaminated with the hepatitis C virus. Of 62,667 women who received anti-D immune globulin during that time, 1% tested positive for current or past exposure to the virus. Liver biopsies on 376 of these women revealed that 98% had liver damage but the damage was not severe. Only 7 women had cirrhosis and two were heavy alcohol users.

Development and progression, Hepatitis C, Contamination, Rho(D) immune globulin

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Correction of anemia with epoetin alfa in chronic kidney disease

Article Abstract:

Studies indicate that recombinant human erythropoietin (epoetin alfa) can be used for the correction of anemia in patients with chronic kidney disease, as its major complication, anemia is caused due to the erythropoietin deficiency. The results also show that a high level of hemoglobin obtained because of the use of epoetin alfa, highly reduces the risk of complications and death from cardiovascular causes as compared to a lower hemoglobin level.

Anemia, Complications and side effects, Erythropoietin, Drug overview

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Rabbit antithymocyte globulin versus basiliximab in renal transplantation

Article Abstract:

Randomized international study was conducted to compare short courses of antithymocyte globulin and basiliximab in patients at high risk for acute rejection or delayed graft function who received a renal transplant from a deceased donor. The findings suggest that intraoperative use of antithymocyte globulin did not lower the incidence of delayed graft function in high-risk population bud did reduce the incidence and severity of acute rejection.

Globulin, Globulins

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