Comparison of warfarin and external pneumatic compression in prevention of venous thrombosis after total hip replacement
Article Abstract:
Warfarin may be more effective than external pneumatic compression in preventing blood clots in the thigh after hip replacement surgery. Of 201 patients undergoing this procedure between 1988 and 1991, 103 were started on warfarin, an anticoagulant, before surgery and 98 were fitted with calf and thigh cuffs that inflated and deflated to stimulate blood flow. Angiography was performed six to 11 days after surgery to detect blood clots either in the thigh or calf. The percentage of patients with blood clots was similar in both groups, but of the patients with blood clots, 46% of those treated with EPC had clots in the thigh, compared to nine percent of the patients who took warfarin. Clots in the calf were more common in patients on warfarin; 19% had clots in the deep veins of the calf, compared to six percent of the patients treated with EPC. Blood clots in the thigh may travel to the lungs, causing pulmonary embolism that may be fatal. This study was prematurely terminated because of the large number of patients in the EPC group who had blood clots in the thigh.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Absence of HIV transmission from an infected orthopedic surgeon: a 13-year look-back study
Article Abstract:
The risk of an HIV-infected surgeon transmitting the virus to patients may be extremely low if recommended infection control practices are followed. Among 2,317 patients who had been operated on by an HIV-infected orthopedic surgeon between Jan 1978 and Jun 1992, 1,174 (51%) were tested for HIV infection. All the patients tested were HIV-negative; two patients who were HIV-positive had been diagnosed with HIV infection before undergoing surgery. None of the surgeon's former patients were found on any AIDS case registries that were examined. The surgeon had voluntarily stopped performing surgery after testing positive for HIV infection in Jun 1991.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
A Clinical Decision Support System for Prevention of Venous Thromboembolism: Effect on Physician Behavior
Article Abstract:
A computer-based clinical decision support system (CDSS) can change a doctor's behavior. In a teaching hospital in Paris, France, researchers used a CDSS that teaches doctors how to prevent abnormal blood clots from forming in patients who have orthopedic surgery. Following the introduction of the CDSS, doctors were more likely to use appropriate anticoagulants to prevent abnormal blood clotting.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Development of vaginal microbicides for the prevention of heterosexual transmission of HIV. A placebo-controlled, double-blind prospective study in healthy female volunteers of dextrin sulphate gel: a novel potential intravaginal virucide
- Abstracts: Identification and Management of Patients with Failed Thrombolysis after Acute Myocardial Infarction. Treatment and outcomes of heart attacks in people with pacemakers
- Abstracts: Semen quality and reproductive endoctrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men
- Abstracts: Number of sexual partners and health lifestyle of adolescents: use of the AMA Guidelines for Adolescent Preventive Services to address a basic research question
- Abstracts: Traditional Intravaginal Practices and the Heterosexual Transmission of Disease. Gender difference in persistent at-risk sexual behavior after a diagnosed sexually transmitted disease