Disseminated Mycobacterium avium infection among HIV-infected patients in Kenya
Article Abstract:
The incidence of disseminated Mycobacterium avium infection in HIV-infected patients in Africa appears to be approximately one percent. Many researchers believed this infection by a bacterium related to the tuberculosis bacterium did not occur in Africa, although it occurs often in HIV-infected patients in the US. Researchers tested 48 people in Kenya with advanced HIV infection for the presence of any species of Mycobacterium. Most had CD4 counts less than 200. Of the 14 people who tested positive, 11 were infected with Mycobacterium tuberculosis and 3 were infected with Mycobacterium avium. Half of the patients with CD4 counts less than 25 were infected, compared with 5% of those with higher CD4 counts. Sixty-four percent of those infected with Mycobacterium died, compared to 38% of those not infected. Two of the three patients infected with Mycobacterium avium died. The low incidence of Mycobacterium avium infection in Africa may result from the fact that HIV patients die before they become severely immunosuppressed.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1995
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Mycobacterial infection in Mexican AIDS patients
Article Abstract:
Mycobacteria other than tuberculosis (MOTT) may be as common as Mycobacterium (M.) tuberculosis among Mexican people with AIDS, though many infections with MOTT may be misdiagnosed. Proper treatment of mycobacterial infection depends upon species identification. Researchers reviewed medical records of 460 people with AIDS who were cared for between 1983 and 1992 at a clinic in Mexico City, Mexico. Of these people, 118 (26%) were diagnosed with a mycobacterial infection. The bacterial species was identified in 45 (38%) of these cases. M. tuberculosis was identified in 13 cases, M. avium complex in 12 cases, and MOTT occurred in 21 cases. The previously reported, low prevalence of MOTT may be due to inadequate diagnosis. Improvements are required in the realm of bacterial isolation, species identification, and testing for drug resistance.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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Some effects of the rising case load of adult HIV-related disease on a hospital in Nairobi
Article Abstract:
Hospital care of HIV patients in Nairobi, Kenya, may compromise hospital access and care of other patients without HIV infection. HIV patients use substantial hospital resources. Researchers compared care at a Nairobi hospital in 1988 and 1989 with care of patients in 1992. Although hospital admissions fell slightly from 1988 to 1992, HIV patients represented 39% of recent admissions, compared to 19% of admissions in 1988. Admissions of HIV-negative patients declined 18% during the study period, and mortality among HIV-negative patients rose from 14% to 23% during the period.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1998
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