Efavirenz- and adefovir dipivoxil-based salvage therapy in highly treatment-experienced patients: clinical and genotypic predictors of virologic response
Article Abstract:
The drugs efavirenz and adefovir dipivoxil appear to be beneficial in HIV patients who no longer respond to nucleotide reverse transcriptase inhibitors. This was the conclusion of a study of 33 HIV patients. Patients who had taken non-nucleoside reverse transcriptase inhibitors were less likely to benefit.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Genotypic correlates of a virologic response to stavudine after zidovudine monotherapy
Article Abstract:
Stavudine will not be effective in HIV patients whose virus has more than one gene mutation for resistance to zidovudine. This probably occurs because resistance to zidovudine also confers resistance to stavudine.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Nonnucleoside reverse transcriptase inhibitor phenotypic hypersusceptibility can be demonstrated in different assays
Article Abstract:
A study aims to determine whether nonnucleoside reverse transcriptase inhibitor (NNRTI) hypersusceptibility could be demonstrated in other types of phenotypic assays, including multicycle assays and enzyme inhibition assays. Conclusions reveal that NNRTI hypersusceptibility is readily seen in multicycle susceptibility assays and in enzyme inhibition assays.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Adherence to postmenopausal hormone therapy during the year after the initial prescription: a population-based study
- Abstracts: Prevalence of Chlamydia trachomatis in urine of male patients with ankylosing spondylitis is not increased. Predictors of functional status in patients with early rheumatoid arthritis
- Abstracts: Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection
- Abstracts: A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression
- Abstracts: Endometrial microbial colonization and plasma cell endometritis after spontaneous or indicated preterm versus term delivery