Elevated plasma factor VIII and D-dimer levels as predictors of poor outcomes of thrombosis in children

Article Abstract:

Levels of factor VIII and D-dimer and additional components of an extensive laboratory thrombophilia panel were evaluated at the time of diagnosis in 144 children with a radiologically confirmed acute thrombotic event. It was found that the elevated levels of plasma factor VIII, D-dimer, or both at diagnosis and a persistent elevation of at least one of these factors after standard-duration anticoagulant therapy predicted a poor outcome in children with thrombosis.

Pediatric diseases, Children, Drug therapy, Thrombosis in children

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Ultrasound energy and the dissolution of thrombus

Article Abstract:

The ultraenergy used in combination with tissue plasminogen activator (t-PA) is shown to have beneficial effect in patients with acute ischemic stroke. The results of prospective randomized trials, confirm that administering a thrombolytic agent in a patient with evolving stroke can be beneficial. However, it is observed that a major limitation of transcranial ultrasonography is attenuation of ultrasound waves by the bones of the cranium.

Care and treatment, Tissue plasminogen activator, Diagnosis, Ultrasonic, Diagnostic ultrasonography

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Mannose-binding lectin variant alleles and the risk of atrial thrombosis in systemic lupus erythmatosus

Article Abstract:

Experiments were conducted on Danish patients with systemic lupus erythmatosus to determine whether mannose binding lectin variant alleles are associated with arterial thrombosis. It was seen that in these patients, homozygosity for mannose-binding lectin variant alleles is associated with arterial thrombosis.

Causes of, Risk factors, Systemic lupus erythematosus

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