Enoxaparin versus unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction

Article Abstract:

Unfractioned heparin is often used as adjunctive therapy with fibrinolysis in patients with ST-elevation myocardinal infarction thus a comparative study is conducted with a low-molecular-weight heparin, enoxaparin with unfractionated heparin. It is observed that in patients receiving fibrinolysis for ST-elevation myocardial infarction, treatment with enoxaparin throughout the index hospitalization is superior to treatment with unfractionated heparin for 48hours but is associated with an increase in major bleeding episodes.

United States, Health aspects, Care and treatment, Comparative analysis, Heart attack, Fibrinolysis, Enoxaparin

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A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism

Article Abstract:

Low-molecular-weight heparin appears to be as effective as regular heparin in treating people with pulmonary embolism. This condition occurs when a blood clot forms in another part of the body and travels to the lungs. Researchers randomly assigned 612 patients with pulmonary embolism to receive daily infusions of regular heparin or injections of low-molecular-weight heparin. At eight days and three months, the incidence of recurrent embolism, bleeding or death was similar in both groups.

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Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism

Article Abstract:

The drug Arixtra may be better than heparin for treating patients who have pulmonary embolism, according to a study of 1,103 patients. Arixtra can be given as a subcutaneous injection, whereas heparin must be given as an intravenous infusion. Consequently, patients must be hospitalized to receive heparin but can go to a clinic for the injection. Pulmonary embolism occurs when a blood clot forms in the legs and then travels to the lungs.

Product/Service Evaluation, Arixtra (Medication)

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