Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle

Article Abstract:

The number and type of immune cells in the vagina appears to be constant throughout the menstrual cycle, as does the number of epithelial cells. This knowledge will allow scientists to study of transmission of HIV via heterosexual intercourse.

Physiological aspects, Menstrual cycle, Vagina

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Amniotic fluid tumor necrosis factor-alpha and the risk of respiratory distress syndrome among preterm infants

Article Abstract:

Infants exposed to tumor necrosis factor-alpha (TNF-alpha) in the uterus may be at greater risk for developing respiratory complications. TNF-alpha is a immune system chemical associated with infection. Amniotic fluid samples were analyzed for TNF-alpha before birth among 136 infants later born prematurely. More infants exposed to TNF-alpha before birth developed respiratory distress syndrome, were hospitalized longer, and were on a ventilator longer than infants with amniotic fluid testing negative for TNF-alpha. Comparisons were made after adjusting for birth weight and other factors.

Health aspects, Risk factors, Infants (Premature), Premature infants, Tumor necrosis factor, Respiratory distress syndrome

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Lipopolysaccharide binding protein and soluble CD14 receptor protein in amniotic fluid and cord blood in patients at term

Article Abstract:

Soluble CD14 receptor protein and elevated levels of lipopolysaccharide binding protein (LBP) in the amniotic fluid and cord blood of patients in labor, with or without infection, may be a general indication of uterine inflammation. These proteins were found in all 33 women at term undergoing cesarean section, 18 of whom were in labor. Elevated levels of LBP were associated with inflammation with or without recovery of microorganisms, and independently associated with the onset of labor. These substances may stimulate inflammation by sensitizing white blood cells.

Analysis, Infection, Measurement, Fetal blood, Cell receptors, Uterus, Amniotic fluid

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