Evidence that human cardiac myocytes divide after myocardial infarction
Article Abstract:
Researchers show that heart muscle can repair itself to an extent after a heart attack. They found that heart muscle cells around the area that was damaged begin dividing to a greater extent than cells in areas that were not damaged.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
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Pim-1 regulates cardiomyocyte survival downstream of Akt
Article Abstract:
The regulation of cellular proliferation and survival by the serine-threonine kinases Pim-1 and Akt is discussed. Some studies show that Pim-1 plays a major role in cardioprotection downstream of Akt.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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Apoptosis in the failing human heart
Article Abstract:
A process of natural cell death called apoptosis appears to occur in heart cells during heart failure. Researchers used microscopy and various chemical methods to study apoptosis in the hearts of 36 patients with heart failure who were receiving a heart transplant and 3 patients who died of heart attacks. Apoptosis of heart cells increased over 200 times the normal rate seen in hearts from 11 people who died of other causes. This was true even though the cells were expressing a protein that protects against apoptosis.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
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