Fasting Insulin and Apolipoprotein B Levels and Low-Density Lipoprotein Particle Size as Risk Factors for Ischemic Heart Disease, Part 2
Article Abstract:
Fasting insulin and low-density lipoprotein cholesterol (LDL-C) particle size and levels may indicate the risk of ischemic heart disease. Researchers measured insulin levels and blood lipids in 85 men with heart disease and 85 men without heart disease. Men with increased fasting insulin apolipoprotein B levels and small, dense particles of LDL-C in the blood had almost six times the risk of heart disease, compared to those with normal levels. Measurement of these heart disease risk factors may improve the predictive value of traditional blood lipid profiles for cardiac disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Can genes prevent atherosclerosis?
Article Abstract:
The case of a 59-year-old woman illustrates the possibility of developing gene therapy to treat atherosclerosis. Even though her cholesterol level was 351 at one testing, she had no sign of atherosclerosis. Physicians discovered that her level of HDL, or 'good' cholesterol, was much higher than normal. This was also true of her blood levels of a component of HDL cholesterol called apolipoprotein A-I. Since her ancestors had lived very long lives, it seems clear that she had a gene that protected her against heart disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1996
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Job strain and risk of recurrent coronary events
Article Abstract:
Research findings show that job strain doubles the risk of recurrent coronary events in patients who were hospitalized for acute myocardial infarction. The role of psychosocial factors related to the means of coping with stress is discussed.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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