Significant fetal-maternal hemorrhage after termination of pregnancy: implications for development of fetal cell microchimerism

Article Abstract:

Women who have an abortion early in the pregnancy may still have fetal blood cells in their blood, a condition called fetal cell microchimerism. The presence of fetal blood cells in a woman's blood has been linked to the development of autoimmune diseases.

Health aspects, Maternal-fetal exchange, Autoimmune diseases, Mosaicism

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High levels of fetal cell-free DNA in maternal serum: A risk factor for spontaneous preterm delivery

Article Abstract:

The relationship between the concentration of fetal cell-free DNA in maternal serum and the duration of pregnancy in women with high risk for preterm delivery due to preterm labor or preterm premature rupture of the membranes is examined. Findings reveal that an increased risk of spontaneous preterm delivery was related to high concentrations of fetal cell-free DNA in maternal serum.

United States, Science & research, Premature labor, Fetal tissues, Premature labour

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Fetal cell identifiers: results of microscope slide-based immunocytochemical studies as a function of gestational age and abnormality

Article Abstract:

Fetal cells may change their antigens as the fetus grows. Antigens are proteins on the surface of every cell. Researchers studied the expression of certain antigens on fetal cells taken from fetal blood. The expression of some of the antigens analyzed declined as the fetus grew older. This means that tests for those antigens would not be able to detect the cells. And that in turn means doctors would not be able to detect fetal cells in the mother's blood. Testing fetal cells in the mother's blood for genetic abnormalities is a non-invasive method for detecting these genetic disorders.

Diagnosis, Fetal blood, Genetic disorders, Diagnosis, Noninvasive, Noninvasive diagnosis

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