Fetal fibronectin as a market to predict the onset of term labor and delivery
Article Abstract:
The presence of fetal fibronectin in the cervical or vaginal mucous of pregnant women at term has high predictability for the onset of labor within 48 hours. Accuracy of prediction exceeds that of the Bishop score, which scores cervical readiness by dilation, effacement, consistency, and position. One hundred women with well-established due dates had samples of vaginal and cervical mucous taken and analyzed two different ways for fetal fibronectin. One method was a test that requires only five minutes, the other was a laboratory enzyme immunoassay test requiring incubation. Both tests agreed 100% of the time on the presence or absence of fibronectin. The presence of fibronectin accurately predicted labor onset within 48 hours in 86% of cases versus 55% for a high Bishop score. The absence of fibronectin accurately predicted no labor within 48 hours in 88% of cases versus 77% for a low Bishop score.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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Fetal fibronectin as a selection criterion for induction of term labor
Article Abstract:
Pregnant women who are found to have fetal fibronectin in fluid from the cervix or vagina may have a greater chance of successful induction of labor. Researchers measured fetal fibronectin in cervical or vaginal secretions from 64 pregnant women whose labor needed to be induced. The 30 women testing positive for fetal fibronectin required less of the inducing drug and their cervices were riper for birth than was the case for the women who did not test positive. The time from induction of labor to delivery was much shorter in women positive for fetal fibronectin. The rate of cesarean delivery and use of vacuum extraction was higher in women testing negative for fetal fibronectin. Fetal fibronectin may be a useful indicator for induction of labor.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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The fast-reacting fetal fibronectin test: a screening method for better prediction of the time of delivery
Article Abstract:
A test for fetal fibronectin in the vagina may improve the accuracy of predicting delivery in pregnant women at their due date. Fetal fibronectin can be detected around the uterine cervix at the onset of labor or following the rupture of fetal membranes. Researchers compared a rapid fibronectin test with the standard cervical scoring system for predicting the time of delivery for 204 women. Women delivered in an average of 1.7 days when fibronectin was detected and the cervix indicated impending delivery. Women delivered in an average of 7.1 days when both values were low.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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