Gene therapy finds welcoming environment in China

Article Abstract:

China became the first country to have approved two drugs based on gene therapy with its State Food and Drug Administration in October 2003 approving Gendicine to treat head and neck cancers. The drug uses an adenovirus to deliver the tumor suppressor gene p53 into tumor cells and in November 2005, the agency approved Shanghai Sunway Biotech's H101, also an adenovirus, which targets cancer cells that lack p53.

China, Product development, Government regulation, Pharmaceutical preparations, Care and treatment, Pharmaceutical industry, Licensing, certification and accreditation, Cancer, Adenoviruses, Gendicine (Medication)

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Therapy on trial

Article Abstract:

The U.S. Food and Drug Administration (FDA) has suspended the gene therapy trial following the death of a participant in an experimental gene therapy clinical trial. The Recombinant DNA Advisory Committee (RAC) is planning to review the death of the Jolee Mohr at the University of Chicago Medical Center.

United States, Health aspects, United States. Food and Drug Administration

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Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion

Article Abstract:

The neuropeptide galanin can modulate seizure activity in vivo super 5,6, and the laminar protein fibronectin is usually secreted through a constitutive pathway. Neuroactive peptide expression and local secretion provides a new gene therapy platform for the treatment of neurological disorders.

Neuropeptides, Nervous system diseases

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