Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
Article Abstract:
A study is done to examine the hypothesis that heparin treatment protects mice from fetal loss caused by aPL antibodies by preventing complement activation on trophoblasts and that anticoagulation, in and of itself, is not sufficient to prevent pregnancy complications in antiphospholipid syndrome (APS). The findings reveal that heparins prevent obstetrical complications in some women with APS as they block activation of complement induced by aPL antibodies targeted to decidual tissues, rather than by their anticoagulant effects.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
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Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism
Article Abstract:
A study was conducted to determine whether fixed-dose, weight-adjusted, subcutaneous unfractionated heparin is as effective and safe as low-molecular-weight heparin is determined for treatment of venous thromboembolism. The findings concluded that fixed-dose subcutaneous unfractionated heparin is as effective and safe as low-molecular-weight heparin in patients with acute venous thromboembolism and is suitable for outpatient treatment.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
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Notice to readers: FDA approval of an alternate dosing schedule for a combined Hepatitis A and B vaccine (Twinrix)
Article Abstract:
GlaxoSmithKline vaccine division has received FDA approval for an alternate dosing schedule for Twinrix a combined vaccine for Hepatitis A and B to be administered as per specifications.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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