Neuroprotective and anti-human immunodeficiency virus activity of minocycline
Article Abstract:
A study is conducted to examine the ability of minocycline, an antibiotic with potent anti-inflammatory and neuroprotective properties, to protect against encephalitis and neuro-degeneration using a rapid, high viral load simian immunodeficiency virus (SIV) model of HIV-associated CNS disease that constitutes a rigorous in vivo test for potential therapeutics. The conclusions suggested that minocycline, a safe, inexpensive, and readily available antibiotic should be investigated as an anti-HIV therapeutic.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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New avenues of exploration for erythropoietin
Article Abstract:
The hormone erythropoietin (EPO), which modulates a broad array of cellular processes, has applicability in a variety of disorders including chronic congestive heart failure. The unique and significant biological role of EPO and its receptor as a cytoprotective agent in both neuronal and vascular systems is described.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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Parkinson disease studies yield insights
Article Abstract:
Increasing evidence of the role of a common pesticide and related compounds in the development of Parkinson disease are presented. Further, how inventions such as exercise and cyclooxygenase 2 inhibitors might address oxidation damage to dopaminergic neurons is studied.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
User Contributions:
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