Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma
Article Abstract:
Hepatocellular carcinoma (HCC, liver cancer) is one of the most common cancers in the world. Infection with hepatitis B virus (HBV) is a major cause of this type of cancer. Alcohol ingestion is also a cause of liver cancer, and the role of cigarette smoking is not clear. Non-A, non-B hepatitis infection may also lead to HCC, and blood tests have confirmed that hepatitis C virus antibodies (anti-HCV) are frequently involved in chronic liver disease. To determine the relationship between hepatitis B and C and liver cancer, blood tests were performed on 185 patients with HCC and 35 patients with metastatic liver cancer (MLC), as well as 432 hospital patients who served as controls. Weakly positive anti-HCV results were more related to MLC than to HCC, suggesting that these results could have been false positives. Strongly positive anti-HCV results were significantly related to HCC (with a relative risk of 6.3), but not to metastatic liver cancer. The association of anti-HCV with HCC was even higher among patients who also tested positive for hepatitis B, suggesting that hepatitis C virus can interact with hepatitis B virus to cause hepatocellular carcinoma. Other studies have also examined the connection between anti-HCV and HCC, but their calculated estimates of relative risk appear to be falsely elevated. The estimate of relative risk from this study is better aligned with the overall incidence of HCC. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1991
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Household budget survey nutritional data in relation to mortality from coronary heart disease, colorectal cancer and female breast cancer in European countries
Article Abstract:
Research into whether Household Budget Surveys (HBS)-derived nutritional patterns are linked with the frequency of occurrence of diseases with strong nutritional elements which are often fatal has focused on colorectal cancer, coronary heart disease and cancer of the female breast. It was established that there is a link between dietary information from HBS and mortality from these diseases. HBS dietary information could play a valuable role in assessing secular changes in dietary patterns with regard to their health repercussions.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1999
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The macronutrient composition of the Greek diet: estimates derived from six case-control studies
Article Abstract:
A study was conducted on 228 men and 610 women in Athens, between 60 and 79 years, to analyze the proportion of energy levels after consuming the standard diet, rich in nutrients. Results showed that the energy absorption is not determined by the age of the person, though older people absorbed less energy. Women absorb more energy from consumption of saturated and monounsaturated fat. The release of energy from protein intake is approximately 19%, from carbohydrates, 37% and from fats, 44%.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1993
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