Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome

Article Abstract:

A trial was conducted on 549 randomly assigned patients with acute lung injury and acute respiratory distress syndrome (ARDS) to compare the effects of higher and lower PEEP (positive end-expiratory pressure) levels on clinical outcomes in these patients. The results showed that in the patients who receive mechanical ventilation with a tidal volume goal of 6ml per kilogram of predicted body weight and an end-inspiratory plateau-pressure limit of 30cm of water, clinical outcomes using higher or lower PEEP levels are similar.

Evaluation, Wounds and injuries, Injuries, Lung volume measurements, Lung volume measurement

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Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome

Article Abstract:

The results of the two studies of recombinant surfactant protein C-based surfactant show that although surfactant therapy improved oxygenation, it did not increase the number of ventilator-free days or reduce mortality in a heterogeneous population of patients with acute respiratory distress syndrome (ARDS). A randomized, double-blind trial involving 448 patients with ARDS was conducted. The use of exogenous surfactant in a heterogeneous population of patients with ARDS did not improve survival.

Care and treatment, Proteins

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The role of ischemic mitral regurgitation in the pathogenesis of acute pulmonary edema

Article Abstract:

A study was conducted on 28 patients with acute pulmonary edema and left ventricular systolic dysfunction and 46 patients without the history of acute pulmonary edema and these patients underwent qualitative Doppler echocardiography during exercise. It was concluded that patients with left ventricular systolic dysfunction; acute pulmonary edema is associated with dynamic changes in ischemic mitral regurgitation and the resulting increase in pulmonary vascular pressure.

Usage, Bacteria, Pathogenic, Pathogenic bacteria, Doppler echocardiography

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