How Escherichia coli infects the urinary tract
Article Abstract:
Urinary tract infections are produced by bacteria growing in the bladder and potentially infecting the kidney. Treatment with appropriate antibiotics usually cures the urinary tract infection. Some women are more susceptible to repeated urinary tract infections inspite of successful treatment. It has been found that receptors on the cells lining the urinary tract are affected by the carbohydrate composition of the cell membrane. This in turn can influence the affinity these receptors have for bacteria, particularly the most common urinary tact bacteria, Escherichia coli. A study found that women experiencing recurrent urinary tract infections have urinary tract cells which bind more easily to bacteria than those of healthy women. Evaluation of secretory cell status, vaccination with proteins to decrease the affinity between the receptors and the bacteria, or the use of solutions similar to the receptors which inhibit the bacterial adhesion may offer improved treatment over prophylactic antibiotic therapy.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1989
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Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors
Article Abstract:
The prevalence and transmissibility of influenza B viruses with reduced sensitivity to neuraminidase inhibitors was assessed at four community hospitals in Japan during the 2004-2005 influenza seasons. The results demonstrated that influenza B viruses with reduced sensitivity to neuraminidase inhibitors could emerge during routine therapy, appearing to be transmitted from person to person.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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