Improvement of depression and triggering of mania by sleep deprivation
Article Abstract:
Sleep deprivation may improve the symptoms of depression in patients whose symptoms are more severe at certain times of day. Many of these patients experience more severe symptoms in the morning. Sleep may actually cause depression - or enhance it - in these patients, and the improvement in mood as the day progresses may indicate that sleep's depressive effect is wearing off. Sleep deprivation can clear the depression completely. However, the depression may return when the patient eventually sleeps again. In this case, partial deprivation - sleeping only a few hours every night - may work, and may actually be an easier life-style change. Sleep deprivation may also trigger mania in individuals with bipolar illness (manic-depression). It is unclear to what extent the manipulation of sleep patterns can be used to treat patients with depression or mania.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
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Persistent Pain and Well-being
Article Abstract:
Pain appears to be a common consequence of psychological illness across cultures. Researchers collected data on pain, psychological illness and disability in 5,438 primary care patients from 15 centers in Asia, Africa, Europe and the Americas. Overall, 22% of the patients reported persistent pain, but the percentages ranged from 5% to 33% depending on the country. Those with pain were more likely to have anxiety and depressive disorders. Persistent pain was consistently linked to psychological illness in all cultures, but not to disability.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Depression as a risk for cancer morbidity and mortality in a nationally representative sample
Article Abstract:
Psychological depression has been studied as a factor influencing the mortality rate among cancer patients. Numerous studies have been done to assess the relative risks for cancer-related illness and death associated with depressive symptoms. Depressive symptoms were not associated with an increased risk for either illness or death related to cancer. The findings of this research cast doubt on other studies that suggest a causal relationship between depression and the risk of cancer.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1989
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