Willingness to participate in HIV-1 vaccine efficacy trials and the effect of media events among gay and bisexual men in New York City: Project ACHIEVE
Article Abstract:
Media coverage may significantly influence participants' willingness to participate in HIV vaccine studies. A total of 698 gay or bisexual HIV-negative men were polled about factors influencing their willingness to participate in an HIV vaccine study. Overall, 68% indicated a willingness to participate. Men polled during intense media coverage of problems with continued HIV vaccine research were not as willing to participate and were more concerned with safety as those polled at other times. Most willing respondents would participate out of concern for the greater community.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1997
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Measuring vaccine efficacy for both susceptibility to infection and reduction in infectiousness for prophylactic HIV-1 vaccines
Article Abstract:
Phase III trials of AIDS vaccines should try to measure a reduction in infectiousness in addition to reduced susceptibility to infection. Many vaccines are not entirely effective in preventing infection but still make the vaccinated person less infectious. An AIDS vaccine could have the same effect. However, most trials do not test for this possibility. This could be done by including the sexual partners of vaccinated participants in the trial. They could be followed without being vaccinated or could be vaccinated along with their partners.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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