Indirect but just as effective

Article Abstract:

Cancer, which could also arise indirectly from defects in the protective cellular mechanisms that repair DNA damage, is studied. It shows that DNA repair defects of various forms and severity initiate genetic instability that affects cancer development, stressing the importance of protecting the integrity of the genome as a tumour-suppression mechanism.

Causes of, Risk factors, DNA repair

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Part-time cop nabs deviant DNA

Article Abstract:

p18, a protein that associates with enzymes that catalyze the attachment of specific amino acids to their cognate tRNAs, has emerged as a potential new tumor suppressor. It also mediates repair of breaks in DNA there by keeping cancer away.

United States, Transfer RNA, Cancer regression

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Microarrays: retracing steps

Article Abstract:

Data obtained from the study of microarray profiles of the human cancer cell lines to predict their response to chemotherapy are discussed. The analysis shows that it is not a reliable method for the purpose.

Genetic aspects, Chemotherapy, DNA microarrays

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