Maternal markers and complications of pregnancy
Article Abstract:
More research is needed to identify biological markers for detecting fetuses that have a high risk of disease. Biological markers are usually substances in the blood that can be measured in blood samples. One such marker is human chorionic gonadotropin. Chorionic gonadotropin is a hormone produced during pregnancy. A 1999 study found that pregnant women with high levels of chorionic gonadotropin had a higher risk of stillbirth, placental abnormalities, and pregnancy-induced hypertension. However, a combination of markers will be most effective to avoid many false-positive results.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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Autoantibodies and pregnancy loss
Article Abstract:
Two 1997 studies shed some light on the link between autoantibodies and recurrent miscarriage. One found that antibodies against naturally occurring phospholipids reduce levels of annexin V, which is a natural anticoagulant found in the placenta. The other found that prednisone was not effective in preventing miscarriage in women with autoantibodies. There are many factors that can contribute to miscarriage and it may be misleading to focus solely on autoantibodies. However, some women with antiphospholipid antibodies may benefit from the anticoagulant drug heparin or aspirin.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
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