Maternal cardiac troponin I levels during normal labor and delivery

Article Abstract:

A protein called cardiac troponin I may be the best indicator of a heart attack in pregnant women. Diagnosing heart attack in pregnant women is a challenge, because many of the proteins that are increased during a heart attack are also increased during pregnancy. This was confirmed in a study of 51 healthy pregnant women in whom blood levels of several proteins were measured before, during and after delivery. Levels of myoglobin, creatine kinase and creatine kinase MB increased two-fold within 30 minutes after delivery. However, levels of cardiac troponin I did not.

Diagnosis, Measurement, Physiological aspects, Heart attack, Pregnant women, Enzymes, Pregnancy

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The effects of dexamethasone and betamethasone on surfactant protein-B messenger RNA expression in human type II pnemocytes and human lung adenocarcinoma cells

Article Abstract:

A study comparing the effect of a single 48-hour exposure to betamethasone or dexamethasone in the cell line and in human type II pneumocytes is presented. The result reveals that dexamethasone and betamethasone achieved similar dose response patterns of surfactant protein-B expression in vitro.

Methods, Case studies, Dexamethasone, Betamethasone, Protein components test

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Characterization of corticosteroid redosing in an vitro cell line model

Article Abstract:

Dexamethasone redosing as a function of time and dose was investigated. Results suggest a residual effect of initial exposure that potentiates redosing allowing significant dose reductions.

Complications and side effects, Drug therapy, Corticosteroids, Dosage and administration, Pregnancy, Complications of, Pregnancy complications, Corticosteroid drugs

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