Mitral annular calcification and the risk of stroke in an elderly cohort
Article Abstract:
Elderly individuals who have mitral annulus calcification (MAC) may have a higher risk for stroke than those who do not. MAC is a chronic disorder characterized by degeneration of the mitral valve of the heart. Of 1,159 individuals between 59 and 90 years old who had not had a stroke, 44 men (10.3%) and 116 women (15.8%) had MAC. Twenty-two individuals (13.8%) with MAC suffered a stroke during an eight-year follow-up period, compared with 51 individuals (5.1%) without MAC. The incidence of MAC was higher among individuals with coronary heart disease or congestive heart failure than among other individuals. Coronary heart disease and congestive heart failure are also risk factors for stroke. The risk of stroke was still twice as high among patients with MAC than among those without, regardless of whether or not they had coronary heart disease or congestive heart failure.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1992
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Prevalence and clinical outcome of mitral-valve prolapse
Article Abstract:
Mitral-valve prolapse (MVP) appears to be much less common than previously reported, and few people with the disease have any significant symptoms. MVP occurs when the mitral valve, between the left atrium and left ventricle of the heart, permits backflow of blood when the ventricle contracts. Researchers examined two-dimensional echocardiograms from 1,845 women and 1,646 men. Only 2.4% of the research subjects had MVP, and the frequencies of atrial fibrillation, cerebrovascular disease, and fainting were similar among those with MVP and those without. Although MVP can increase the risk of stroke, fainting, heart valve infections, and other conditions, the condition appears to be relatively benign in most people.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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Parental Atrial Fibrillation as a risk factor for Atrial Fibrillation in offspring
Article Abstract:
The study determines whether parental Atrial Fibrillation (AF) increases the risk for the development of offspring AF. The different risk factors for AF includes advancing age, diabetes, hypertension, heart failure and valvular heart disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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