Natural History of Progression After PSA Elevation Following Radical Prostatectomy
Article Abstract:
Many men who have their prostate removed to treat prostate surgery may not develop a recurrence even if their prostate-specific antigen level (PSA) begins to rise. In a study of 1,997 men who had a prostatectomy for prostate cancer and were followed for up to 15 years, the survival rate 15 years after surgery was 82%. In 15% of the men, PSA levels began to rise sometime after surgery. About one-third of these men developed metastatic disease an average of eight years after PSA levels began to rise. Several biochemical characteristics predicted which men would develop metastatic disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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Pretreatment PSA velocity and risk of death from prostate cancer following external beam radiation therapy
Article Abstract:
An attempt is made to assess whether a greater than 2.0-ng/mL increase in prostate-specific antigen (PSA) level during the year prior to diagnosis is significantly associated with prostate cancer-specific mortality following radiation therapy (RT). It is concluded that the increase in PSA level during the year prior to diagnosis is associated with a significantly higher risk of death due to prostate cancer following RT despite having low-risk disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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Risk of prostate cancer-specific mortality following biochemical recurrence after radical prostatectomy
Article Abstract:
A study is conducted to define risk factors for prostate cancer death following radical prostatectomy and to develop tables to risk stratify for prostate cancer-specific survival. It is concluded that clinical parameters could help risk stratify patients for prostate cancer-specific mortality following biochemical recurrence after radical prostatectomy.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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