Neurotoxicity related to the use of tropical tretinoin (Retin-A)

Article Abstract:

Tretinoin applied to the skin may cause neuropsychiatric symptoms in rare cases. Tretinoin is also known as Retin-A, a commonly used acne treatment. Patients with chronic hepatitis C, which may damage the liver, may not be able to process vitamin A-type drugs such as Retin-A, and toxic reactions may result. A 39-year-old woman with mild depression and chronic hepatitis C borrowed a friend's Retin-A cream to treat her acne. She consulted a doctor after she began to experience lack of coordination and difficulty speaking. She did not mention her use of Retin-A. As time went on, she developed other neurologic symptoms and had to use a walker. She finally mentioned using Retin-A after doctors had ruled out other conditions. Her symptoms went away after she stopped using the Retin-A cream.

Causes of, Complications and side effects, Physiological aspects, Hepatitis C, Tretinoin, Nervous system diseases, Retin-A (Medication)

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MODERN CLINICAL APPLICATIONS RELATED TO CHINESE TRADITIONAL THEORIES OF DRUG INTERACTIONS

Article Abstract:

The article describes how ancient Chinese understandings of how drugs interact with one another is being adopted, and confirmed, by Western medical professionals in the 20th century. Topics include the Chinese notions of drug interactions, such as xiang wei and xiang xu, which refer to particles respect or need for each other, and the Western techniques to validate Chinese prescriptions.

United States, China, Research, Study and teaching, Drug interactions, Medicine, Chinese, Traditional Chinese medicine, Pharmaceutical research

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Firearm Related Deaths: The Impact of Regulatory Reform

Article Abstract:

Gun control laws in Victoria, Australia after 1988 produced dramatic reductions in firearm related deaths, particularly suicides.

Victoria, Analysis, Evaluation, Firearms, Gun laws, Gun violence

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