Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease
Article Abstract:
An investigation on whether levels of oxidized low-density lipoprotein (LDL) measured with use of monoclonal antibody E06 reflect the presence and extent of obstructive coronary artery disease, defined as a stenosis more than 50 percent of the luminal diameter is presented. The results reveal that circulating levels of oxidized LDL are strongly associated with angiographically documented coronary artery disease, particularly in patients 60 years of age or younger.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
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Treatment of Paget's disease - taming the wild osteoclast
Article Abstract:
Continuous research in understanding the cellular and molecular biology of the osteoclast have led to the development of two drugs for the treatment of Paget's disease of bone. The efficacy of osteoprotegerin and zoledronic acid in the treatment of Paget's disease and also the risks involved in with these two agents are discussed.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
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