Persistence of multiple serovars of Neisseria gonorrhoeae
Article Abstract:
Use of two mathematical models on the transmission of Neisseria (N.) gonorrhoeae show that multiple strains of the bacteria persist over several years and that which strains persist varies between heterosexual and homosexual populations. One model assumes homogeneity of both population and form of sexual contact, for example homosexual men practicing only anal sex. The other model assumes heterogeneity of population and form of sexual contact, for example men and women practicing both vaginal and anal sex. In both models, two strains of N. gonorrhoeae with different rates of transmission are introduced. The models were used to explain changes in the population and distribution of N. gonorrhoeae strains seen in real data collected over six years. Overall, the number of strains contributing to the majority of cases dropped, and two strains increased significantly. Applying the models to sexual behavior suggests that bisexual practices are becoming less of a factor in the transmission of N. gonorrhoeae.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1993
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Mathematical modeling of epidemic syphilis transmission: implications for syphilis control programs
Article Abstract:
Mathematical models of syphilis transmission may help to determine why epidemics occur and how they may be prevented. Researchers developed a mathematical model of a hypothetical population of 11,000 young and middle age adults over four years. Variables modelled were the probability of transmission, duration of infection, number of sexual contacts per week, and acquired immunity. The model showed that epidemics of syphilis may depend on a small group of people with a high number of sexual partners. This group might consist of just 14 people if each person had 300 sexual partners per year. Epidemics of syphilis may resolve on their own as a result of acquired immunity after infection. Elimination of crack cocaine houses may prevent syphilis epidemics by limiting the number of people with lots of sexual partners.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1996
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Neisseria gonorrhoeae MS11mkC Opacity Protein Expression In Vitro and During Human Volunteer Infectivity Studies
Article Abstract:
Neisseria gonorrhoeae MS11mkC has 11 opacity (Opa) proteins whose expression changes from transparent to opaque during the course of the infection. Neisseria gonorrhoeae is the bacterium that causes gonorrhea.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 2000
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