Predictive value of early virologic response in HIV/hepatitis C virus-coinfected patients treated with an interferon-based regimen plus ribavirin
Article Abstract:
A study was conducted to assess the utility of an early virologic response (EVR) to predict a sustained virologic response (SVR) to hepatitis C virus (HCV) therapy in a group of HIV/HCV-coinfected patients. The findings reveal that the rules of reduction of 2 log of the viral load at week 12 of HCV therapy in coinfected patients have the same value as those in monoinfected patients and high positive predictive value (PPV) provides a goal to motivate adherence during the therapy and stimulates patients to continue the treatment.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
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Evolution of HIV resistance mutations in patients maintained on a stable treatment regimen after virologic failure
Article Abstract:
A study was conducted to compare the rate of emergence of thymidine analogue mutations (TAMs) and major protease inhibitor mutations in adherent patients who remained on stable treatment with a thymidine analogue and/or protease inhibitor after the onset of virologic failure. It is concluded that major protease inhibitor mutations arose more frequently and rapidly than did TAMs in patients with sustained virologic failure who received lamivudine
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Cervical shedding of HIV-1 RNA among women with low levels of viremia while receiving highly active antiretroviral therapy
Article Abstract:
A cohort of women is investigated to identify the factors associated with cervical HIV-1 RNA shedding in women with low and undetectable plasma HIV-1 RNA. The analysis has described the risks for genital HIV-1 RNA shedding in women with low/undetectable plasma virus.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
User Contributions:
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