Projections of hypertension-related renal disease in middle-aged residents of the United States
Article Abstract:
Most middle-aged patients with hypertension-related renal (kidney) disease in the US may not develop end-stage renal disease (ESRD). Individuals with hypertension have a higher risk of developing renal disease or cardiovascular disease than other individuals. A study estimated the number of middle-aged US residents with hypertension who will develop mild kidney disease or ESRD per year. Among 1.8 million middle-aged US residents with hypertension, an estimated 140,000 will develop mild kidney disease and an estimated 5,300 will develop hypertension-related ESRD per year. African-Americans have a higher risk of developing hypertension, mild kidney disease or ESRD than other individuals. Men have a higher risk of developing these disorders than women.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
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Aspirin and Risk of Hemorrhagic Stroke: A Meta-Analysis of Randomized Controlled Trials
Article Abstract:
The benefits of aspirin treatment in patients with cardiovascular disease probably outweigh the risks. Because aspirin prevents blood clotting, it can increase the risk of bleeding. Researchers analyzed 16 clinical trials covering 55,462 patients with cardiovascular disease who received aspirin or a placebo. Overall, aspirin reduced the mortality rate by 15%, the rate of heart attack by 32%, and the rate of stroke by 12%. It also increased the risk of hemorrhagic stroke, but the number of people affected was much smaller than the number who benefited from aspirin.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Risk of end-stage renal disease in diabetes mellitus: a prospective cohort study of men screened for MRFIT
Article Abstract:
Diabetes mellitus appears to substantially increase the risk of end-stage renal disease (ESRD). Researchers analyzed the incidence of ESRD in 332,544 men in the Multiple Risk Factor Intervention Trial (MRFIT) between 1975 and 1990. Compared to non-diabetics, diabetics had 92 times the risk of developing ESRD caused by diabetes and also 3 times the risk of ESRD caused by other factors. Their overall risk of ESRD from any cause was 9 times the risk in non-diabetics. Adequate blood glucose control could prevent many of these cases of ESRD.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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