Radiographic progression of hospital referred osteoarthritis of the hip
Article Abstract:
Certain clinical and radiographic features may help identify patients who may develop rapidly progressive osteoarthritis of the hip upon referral to a hospital for treatment. Osteoarthritis is a noninflammatory joint disease that mainly affects elderly individuals. A study followed 136 patients who were referred to a hospital for treatment of osteoarthritis of the hip for an average of 27 months. Fifty-three percent of 192 osteoarthritic hips were surgically replaced an average of 14 months after referral to the hospital. Rapid radiographic progression of the disease was associated significantly with an atrophic bone response, or wasting of bone tissue. Women were more likely than men to experience rapid progression of the disease. Progression was also faster in patients who were older when they developed the disease.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1993
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Factors affecting radiographic progression of knee osteoarthritis
Article Abstract:
X-rays appear to be useful in diagnosing disease progression in patients with knee osteoarthritis. A group of 188 mostly elderly patients with 350 arthritic knee joints among them were followed for 1 to 5 years. Patients were assessed at six-month intervals and knee X-rays were taken at least annually. Increased damage was seen on X-ray in 72% of knee joints. Forty-eight percent reported increased symptoms and 23% reported improvement during the study. Bone erosion and joint space narrowing correlated with worsening symptoms and decreased function. Swelling, warmth, and calcium pyrophosphate crystals in the synovial fluid were also associated with a worsening of the patient's condition.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1995
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Chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in progressive versus non-progressive osteoarthritis
Article Abstract:
The amounts of condroitin sulphate (CS), keratan sulphate (KS), hyaluronan (HA) and total glycosaminoglycans (GAG) in knee-joint fluid do not appear to predict which osteoarthritis patients will experience progressive joint degeneration. Researchers measured amounts of CS, KS, HA, and GAG in joint fluid samples from the osteoarthritic knees of 70 patients at their first visit. Patients were followed for an average of 2 years. Forty-five patients showed osteoarthritic progression on X rays and 25 patients did not. Amounts of CS, KS, HA, and GAG did not predict which patients would have progressive arthritis.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1997
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