Safety and Toxicity of Nonoxynol-9 Gel As a Rectal Microbicide
Article Abstract:
Nonoxynol-9 (N-9) appears to be relatively safe for gay men who have anal sex to use. This drug was developed to prevent HIV infection. It is inserted into the vagina or rectum and can be used by women and gay men. Twenty-five HIV-negative and 10 HIV-positive gay men used N-9 gel or a placebo gel alternatively during anal sex. Rectal exams and rectal biopsies at 1, 2, 5, and 6 weeks showed no rectal ulcers as a result of the treatment. However, 89% of the men had abnormal tissue changes after using N-9 compared to 69% after using the placebo gel.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
Security on the Internet: is your system vulnerable?
Article Abstract:
Ten basic steps performed routinely can help prevent unwanted access and contamination of an organization's Internet system. These steps include developing unusual and routinely changed passwords, installing current editions of all software including antivirus software, and monitoring system directories for unknown programs. Other safeguards include monitoring physical access, system access, and data locations. A buffer computer restricting Internet access can also protect against abuse.
Publication Name: Nursing Management
Subject: Health
ISSN: 0744-6314
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Standardizing the care of bronchiolitis. Return to sender
- Abstracts: Social and economic dimensions of environmental policy: lead poisoning as an example. Reckonitis: a cognitive deficit of social origin
- Abstracts: Something new out of Africa. Nomads in the Horn of Africa. Africa on the precipice: an ominous but not yet hopeless future
- Abstracts: Shades of inspiration. Tech toys that promote creativity. Naked confidence!
- Abstracts: Neurotoxicity related to the use of tropical tretinoin (Retin-A). Firearm Related Deaths: The Impact of Regulatory Reform