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Seeing the forest for the trees

Article Abstract:

Transcriptional responses to several antidepressants, antipsychotics and opioid-receptor agonists in human primary neurons assisted in determining whether the treatments administered at non-toxic doses produce distinct expression profiles, which correlate with clinical efficacy. The physiological consequences of treatments from their gene expression profiles could be predicted by the classification tree (CT) and random forest (RM) methods.

Author: Frantz, Simon

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004

Gene expression, Toxicogenomics

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Short-circuit recovery from spinal injury

Article Abstract:

The significance of the propriospinal neurons in the short-circuit recovery after a spinal cord injury, even when descending pathways from the brain are damaged, is discussed.

Author: Stelzner, Dennis J.

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2008

Care and treatment, Neuroplasticity, Spinal cord injuries

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Subjects list: Research, Neurons

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