Selection of antiretroviral therapy guided by genotypic or phenotypic resistance testing: An open-label, Randomized, Multicenter Study (PhenGen)
Article Abstract:
The genotype/virtual phenotype (vPt) and real phenotype (rPt) for choosing a new highly active antiretroviral therapy regimen at failure is studied with the help of a phenotype/genotype (PhenGen) open-Lbel, randomized, multicenter study. The principle characteristics (including sex, age, clinical status, number of prior regimens and antiretroviral medications, and mode) of patients changing therapy did not differ from those of patients who continued the prescribed regimen.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
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Influence of genotype 3 hepatitis C coinfection on liver enzyme elevation in HIV-1-positive patients after commencement of a new highly active antiretroviral regimen
Article Abstract:
The independent role of hepatitis C virus (HCV) genotype 3 in liver transaminase elevation following antiretroval regimens is still controversial. HIV-positive patients coinfected with HCV genotype 3 displayed a higher risk of relevant hepatotoxicity, independently from other clinical variables and the impact of HCV genotype outweighed the role of drugs in determining hepatoxicity.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Mortality for liver disease in patients with HIV infection: a cohort study
Article Abstract:
HIV patients who drink excessive amounts of alcohol or who become infected with the hepatitis B virus have a high risk of death from liver disease. This was the conclusion of a study of 308 HIV patients who died, 35 of whom died of liver failure.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
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