Selective reduction of multifetal pregnancies to twins improves outcome over nonreduced triplet gestations

Article Abstract:

Reducing multiple pregnancies to twins appears to improve outcomes to that of nonreduced twin pregnancies and result in better outcomes than nonreduced triplet pregnancies. Researchers compared outcomes of 54 triplet pregnancies, 59 twin pregnancies resulting from pregnancy reduction, and 88 nonreduced twin pregnancies. In all cases pregnancy resulted from in vitro fertilization and exceeded 24 weeks gestation. Compared with triplet pregnancies, women with twin pregnancies were less likely to develop preeclampsia, more likely to be delivered after 36 weeks gestation, and birth weights averaged 100 grams more after correction for gestational age.

Care and treatment, Abortion, Twins

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Multiple gestations from in vitro fertilization: successful implantation alone is not associated with subsequent preeclampsia

Article Abstract:

Multiple implantation does not appear to be the cause of the increased incidence of preeclampsia seen in women having in vitro fertilization. Researchers compared the incidence of preeclampsia in 38 women with in vitro conception of triplet pregnancies with 38 similar women with twin pregnancies resulting either from fetal reduction of higher order pregnancies or spontaneous loss. Forty-five percent of the triplet group had preeclampsia versus 16% of the twin group. One-quarter versus 8% had severe preeclampsia. This suggests that the number of successfully implanted embryos does not affect the subsequent development of preeclampsia.

Risk factors, Preeclampsia, Fertilization in vitro, Human, Human fertilization in vitro

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How accurate is fetal biometry in the assessment of fetal age?

Article Abstract:

Measuring specific fetal body parts can give a good indication of the gestational age of the fetus. Researchers used ultrasound scans to measure specific fetal body parts in 152 single, 67 twin and 19 triplet pregnancies resulting from in vitro fertilization. Unlike normal pregnancies, the date of conception from in vitro fertilization is precisely known. Head circumference best predicted gestational age, even more so when abdominal circumference and femur length were added. This predicted gestational age within three days of the actual age.

Evaluation, Measurement, Fetus, Gestational age

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