Severe thrombocytopenia as a presenting manifestation of Kawasaki disease

Article Abstract:

The case of a six-year-old girl with thrombocytopenia illustrates that this condition may be a sign of Kawasaki disease (KD). Thrombocytopenia is an abnormally low number of blood platelets. KD is a childhood illness characterized by a range of symptoms including fever, a body rash, inflammation of the lining in the mouth, and swollen lymph nodes in the neck. The patient had a fever, a red rash between her legs, abdominal pain, diarrhea, and swollen lymph nodes in her neck. Blood tests revealed an extremely low platelet count and abnormal blood clotting. During the next two days, the rash spread over the patient's body and she developed swelling in her hands and feet. She developed increased blood in the mucous membrane lining of her eyes and a strawberry-like tongue. She was diagnosed with KD and treated with intravenous gamma-globulin and aspirin.

Diagnosis, Causes of, Kawasaki disease, Kawasaki syndrome

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Thrombocytopenia in neonates with trisomy 21

Article Abstract:

Newborns with trisomy 21 (Down's syndrome) appear to have an increased risk of mild thrombocytopenia. Thrombocytopenia is an abnormally low number of blood platelets. Researchers reviewed the medical records of 65 newborns who had blood platelets counts within 48 hours of birth. Twenty-five had Down's syndrome. The median platelet count was significantly lower in infants with Down's syndrome than in the other infants. Seven Down's syndrome infants and none of the other newborns were thrombocytopenic. Most thrombocytopenic infants also had congenital heart defects. All cases of thrombocytopenia were mild and did not cause bleeding complications. Although the association between Down's syndrome and some blood disorders is well-recognized, an increased risk of thrombocytopenia in this patient group has rarely been reported.

Risk factors, Physiological aspects, Down syndrome

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Ovarian Cyst and Torsion in a Young Infant

Article Abstract:

An ovarian cyst in a 6-week-old girl illustrates this interesting pediatric condition. The child developed an abdominal mass and had difficulty with feeding. Ultrasound examination revealed a cystic structure in the ovary, which was removed surgically. Ovarian cysts can cause the ovary to become twisted, necessitating immediate surgery. Untwisted cystic ovaries may be drained. Autopsy studies indicate that 34% of female infants and stillborns may have this condition.

Ovaries, Ovarian cysts

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