Short-course, low-dose amphotericin B lipid complex therapy for visceral leishmaniasis unresponsive to antimony
Article Abstract:
Visceral leishmaniasis seems completely responsive to low-dose short-term treatment with amphotericin B lipid complex. This protozoal infection, also known as black fever or kala-azar, has become less responsive to the traditional treatment using antimony. Intravenous amphotericin B was given in three different dosages to 60 patients for 5 days. After 14 days, all were considered free of parasites. A small percentage of patients taking the lower dose had a relapse, but re-treatment with a higher dose was confirmed successful after a 6-month follow-up.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1997
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Preventing fungal infections in patients with stem-cell transplants
Article Abstract:
The drug itraconazole may be more effective than fluconazole for preventing fungal infections in people who have received a stem cell transplant, according to a study of 140 patients. However, itraconazole was more likely to cause nausea, vomiting, diarrhea, and abdominal pain than fluconazole. It may still be the best choice because some fungi are becoming resistant to fluconazole.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2003
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Itraconazole and amphotericin B to treat fungal infections in patients with cancer who are receiving chemotherapy
Article Abstract:
Itraconazole is as good as amphotericin B for preventing fungal infections in cancer patients who have had chemotherapy and has fewer side effects. Chemotherapy often damages the immune system, making the patient susceptible to infection.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
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