Skeletal evidence of osteoarthritis: a palaeopathological perspective

Article Abstract:

Evaluating patterns of osteoarthritis in skeletons from postmortems, archeological digs, and nonhuman primates can increase understanding of this disease. However, drawing firm conclusions is difficult because we lack sufficient data on lifestyle and clinical history of disease progression. For this reason, connections between daily activity and degenerative effects on joints cannot be made even though patterns of joint involvement can be seen that differ between populations. Among nonhuman primates, evidence suggests that walking on the hind limbs adversely affects the spine, but age is a confounding factor, and at least one species of monkey that goes on all fours commonly shows spinal degeneration. It would be helpful to standardize systems for scoring joint degeneration, study more skeletons at postmortems where age, occupation, and symptoms are known, and study more zoo primates where, again, information about the animal's age and activities are known.

Research, Paleopathology

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Association of hand and knee osteoarthritis: evidence for a polyarticular disease subset

Article Abstract:

Patients with osteoarthritis (OA) in the hand also seem to have OA in the knee, particularly with increasingly severe disease. Doctors analyzed hand and knee X-rays of 269 female and 426 male volunteers over age 40 for evidence of OA and for an association between OA of the hand and knee. Overall, there was an association between advanced knee and hand OA at all the joints measured except the wrist to index finger joint. This association increased as the number of joints involved increased. The incidence of disease in both the knee joints and the joints between the fingers was 32.6% for women and 29.4% for men. The incidence of disease in both the knee joint and two hand joints was 26% for women and 22% for men. The older participants had a higher incidence of joint disease at multiple sites.

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Radiographic assessment of hip osteoarthritis progression: impact of reading procedures for longitudinal studies

Article Abstract:

The Kellgren and Lawrence grading system for evaluating joint X-rays can produce different results depending on whether the radiologist compares it to other X-rays of the patient and knows the chronological order of the X-rays. Research on the progression of arthritis should use one standard method for reading X-rays.

Usage, Hip joint, Diagnosis, Radioscopic, Radioscopic diagnosis

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