Staging laparotomy in Hodgkin's lymphoma: 1979 to 1988

Article Abstract:

To obtain a more precise definition of the location of intra-abdominal Hodgkin's disease, exploratory surgery may be performed for improved staging (a system for describing the extent of disease). Although various imaging methods have recently been used to evaluate patients with Hodgkin's lymphoma, none is able to reliably predict disease in the spleen, liver and upper abdominal lymph nodes. A retrospective study was undertaken to evaluate the effectiveness of clinical staging. A total of 94 patients were studied; all were newly diagnosed to have Hodgkin's lymphoma and underwent staging laparotomy. Prior to surgery 86 patients had lymphangiography (X-ray study of the lymphatic system) and 53 patients had computed tomography of the abdomen. Both procedures had an accuracy rate of 76 percent. There were no deaths following staging laparotomy. The 30-day morbidity was 17 percent, with 8 percent of patients experiencing major complications and 10 percent experiencing minor complications. The late complication rate (beyond 30 days) was 5 percent. Laparotomy prompted changes in the staging of Hodgkin's lymphoma in 28 percent of cases, resulting in treatment changes in 18 percent of patients. The authors conclude that in selected patients, staging laparotomy is a safe and accurate method of evaluating Hodgkin's lymphoma within the abdomen. (Consumer Summary produced by Reliance Medical Information, Inc.)

Evaluation, Diagnosis, Hodgkin's disease, Surgery, Tumor staging, Cancer staging, Abdomen, Laparotomy

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Rapidly progressive sacroiliitis in a patient with lymphocytic lymphoma

Article Abstract:

A patient with lymphocytic lymphoma developed rapidly progressive sacroiliitis. Sacroiliitis is inflammation of the sacroiliac joint in the lower back. A 61-year-old woman with lymphocytic lymphoma consulted a rheumatology clinic when she developed stiffness in her hip, back and neck. She started experiencing stiffness in her lower back and hips approximately six months earlier. She was confined to a wheelchair at the time of her appointment at the rheumatology clinic. A computed tomography (CT) scan revealed that she had sacroiliitis. She was treated with prednisone and sulfasalazine over a five-week period. After developing a kidney stone, she was switched from sulfasalazine to azathioprine. Cancer patients may develop different musculoskeletal disorders as a result of cancer metastasis.

Case studies, Complications and side effects, Bone diseases, Lymphomas, Muscle diseases, Muscular diseases

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Non-Hodgkin's lymphoma in homosexual men in the San Francisco Bay Area: occupational, chemical, and environmental exposures

Article Abstract:

Chemical exposures may decrease the risk of non-Hodgkin's lymphoma (NHL) in HIV-positive gay men and increase the risk among HIV-negative gay men. HIV-negative men were slightly more likely to have been exposed to herbicides and less likely to have worked in managerial, professional, technical, or sales jobs. HIV-positive men were less likely to have worked in production or repair jobs.

United States, Statistical Data Included, Environmental aspects, HIV patients, Non-Hodgkin's lymphomas, Gay men

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