Steroid hormone effects on the proliferation of human ovarian surface epithelium in vitro

Article Abstract:

Steroid hormones may not cause ovarian epithelial cell proliferation in tissue cultures. Epithelial cells of the ovary proliferate into ovarian cancer in 90 percent of cases despite appearing benign and tissue models are important for understanding the mechanism of abnormal tissue growth. Researchers analysed the response to steroid hormones in human ovarian epithelium cell cultures. The steroids 17 beta-estradiol, progesterone, dihydrotestosterone, and dexamethasone were combined with cell cultures. Dosing with steroid hormones did not seem to affect cell growth. However, estrogen receptors were found in premenopausal cells but were absent on postmenopausal tissue.

Health aspects, Physiological aspects, Ovarian cancer, Cell proliferation, Epithelium, Steroid hormones

---

Biopsy findings in five hundred thirty-one patients with atypical glandular cells of uncertain significance as defined by the Bethesda system

Article Abstract:

Atypical glandular cells of uncertain significance detected on a Pap smear may indicate an increased risk for both pre-malignant and malignant lesions. Cervical biopsies on 531 patients with these abnormal cells, as identified by the Bethesda classification system, revealed 36% with invasive or non-invasive lesions. Most were non-invasive squamous lesions. Seventeen percent were invasive, and most of these were glandular in origin, rarely seen when only squamous cell abnormalities are noted. Bethesda system subcategories were found to adequately predict existing disease.

Usage, Cervix uteri, Pap test, Cervix uteri biopsy

---

The significance of atypical glandular cells on routine cervical cytologic testing in a community-based population

Article Abstract:

It may be necessary to closely follow all women whose Pap smear shows atypical glandular cells of undetermined significance. Of 64 women with this diagnosis who had a biopsy, 39 had cervical disease and 5 had cervical cancer.

Cytology

Similar abstracts:

• Abstracts: The effect of training on the provision of elective abortion: a survey of five residency programs. Safety of intra-amniotic digoxin administration before late second-trimester abortion by dilation and evacuation
• Abstracts: Emerging infections on center stage at first major international meeting. AIDS in South Africa Takes Center Stage
• Abstracts: Prospects for an AIDS vaccine. Reversion of CTL escape-variant immunodeficiency viruses in vivo
• Abstracts: Pharmacologic Treatment of the Irritable Bowel Syndrome: A Systematic Review of Randomized, Controlled Trials
• Abstracts: Pulsatile pelvic masses: options for evaluation and management of pelvic artiovenous malformations. Go, girl!

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.