Prevalence of measles antibodies in asymptomatic human immunodeficiency virus-infected patients

Article Abstract:

Within the last two years there has been a dramatic increase in the number of cases of measles. During 1989 alone, the Centers for Disease control received reports of 248 outbreaks involving a total of 18,193 cases of measles. Eighty-three percent of these cases of measles occurred in people under the age of 20. Several severe cases of measles were reported in children infected with the human immunodeficiency virus (HIV, the virus that causes AIDS). Therefore, it was recommended that children infected with the HIV be immunized with vaccines for measles, mumps and rubella. This recommendation has lately been extended to include adults with HIV infection. To determine the relationship between HIV infection and measles, 105 adults with HIV infection were tested for measles antibody. Fifteen of the patients reported that they had never had measles or measles vaccination, 46 had had measles but had not been given the vaccine, 18 had been vaccinated but had not had measles, and 26 had both the vaccine and measles. When blood samples from each subject were tested it was found that all but one of the patients had measles antibody. The amount of measles antibody present in the blood was not related to patient age, history of measles or vaccination, or CD4+ lymphocyte count (a measure of the severity of HIV infection). Until further studies can be performed to determine if the measles antibodies in these patients are protective against measles, it is recommended that adults with HIV infection who are exposed to measles be treated with immune globulin. (Consumer Summary produced by Reliance Medical Information, Inc.)

Prevention, Complications and side effects, Physiological aspects, HIV infection, Measles

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HIV infection in women: an observational study of clinical characteristics, disease progression, and survival for a cohort of women in Chicago

Article Abstract:

The progression of HIV infection to AIDS and death in women appears to be similar to that in men. Researchers followed 82 women who were diagnosed with HIV infection at a Chicago hospital between 1986 and 1992. Almost half were white, 40% were black and 12% were Hispanic. Sixty percent had become infected through sexual intercourse and 22% through intravenous drug abuse. The most common opportunistic infections were Candida infections, Pneumocystis carinii pneumonia and Mycobacterium avium complex infection. None of the women developed Kaposi's sarcoma, a type of skin cancer that often occurs in HIV-infected men. However, the women were more likely to develop Candida infections. This may occur because Candida often grows in the vagina. The median survival time of 27 months was comparable to the median survival time of 26.3 months in HIV-infected men.

Women, Development and progression, HIV infection in women

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