Teasing out the tangles

Article Abstract:

Study is presented to provide an evidence that neurofibrillary tangles (NFTs) are not causally linked to cognitive decline and they instead favor the hypothesis that soluble tau may be responsible for the loss of neurons and impaired memory function in Alzheimer disease. Analyses of transgenic mice expressing mutant tau indicate that A(beta) can promote formation of NFTs, suggesting that neurotoxicity in Alzheimer disease is caused by a number of events that starts with elevated production of A(beta).

Science & research, Research, Neurofibrils

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The amyloid code

Article Abstract:

Many scientists believe that the protein triggers a series of steps, dubbed the amyloid cascade that leads to the memory loss and dementia in those afflicted with Alzheimer disease. It is believed that in familial or early onset forms of the disease, mutations in the amyloid precursor protein and the enzymes that clip it to form amyloid-beta, lead to a massive overproduction of amyloid-beta and a swift descent into disease.

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AIDS meeting spotlights pills to prevent infection

Article Abstract:

The recurring theme of the sixteenth international AIDS conference held at Toronto in August 2006,was that gels, creams and pills that can prevent HIV infection are the most promising new tools to fight HIV/AIDS. Participants at the meeting also discussed the use of cervical barriers, such as diaphragms, and suppressing herpesvirus infections, which increase HIV risk by up to three times.

Conferences, meetings and seminars, Prevention, HIV infection, HIV infections, AIDS (Disease)

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