The fetal central venous pressure waveform in normal pregnancy and in umbilical placental insufficiency
Article Abstract:
A new ultrasound technique called phase-locked echo tracking can measure blood pressure in the vena cava of the fetus. The technique measures changes in the diameter of the blood vessel lumen and thus records the pressure wave that passes through the vessel with each beat of the heart. The new technique may prove useful in diagnosing fetal compromise. Measurements were taken on 70 normal fetuses between 20 and 40 weeks gestation in order to establish normal values. Values were then compared with 54 fetuses from pregnancies with complications such as maternal hypertension, suspected growth failure, preterm labor, hemorrhage, maternal diabetes mellitus, and maternal kidney disease. Ten of the fetuses from the complicated group had normal waveforms. None of them had fetal distress, intrauterine growth retardation (IUGR), or were admitted to intensive care. Twenty of the fetuses with abnormal tracings had fetal distress, 31 had IUGR, and 21 were admitted to neonatal intensive care.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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Elevated levels of lipoprotein(a) in women with preeclampsia
Article Abstract:
Lipoprotein(a) may play a role in the blood clotting abnormalities seen in pregnant women with preeclampsia. Preeclampsia is a serious complication of pregnancy characterized by hypertension and excessive blood clotting. Researchers measured lipoprotein(a) levels in blood samples taken from 24 normal pregnant women, 18 pregnant women with mild preeclampsia and 8 pregnant women with severe preeclampsia. Lipoprotein(a) levels were substantially higher in the women with preeclampsia.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
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Microvascular endothelial cell activation is present in the umbilical placental microcirculation in fetal placental vascular disease
Article Abstract:
The vascular disease in the fetal umbilical placental circulation is associated with an increase in the expression of intercellular adhesion molecule-1 and platelet endothelial cell adhesion molecule-1 by microvessel endothelial cells. The locally released factors cause injury and activation to microvessel endothelial cells.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
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