The role of gonadotropins in ovulation induction

Article Abstract:

Commercially prepared follicle-stimulating hormone (FSH) may be a better choice for ovulation induction (OI) than menotropins. Physicians may need to evaluate each infertility patient individually to provide the most effective and efficient gonadotropin therapy for controlled hyperstimulation of the ovary. Individual patients may vary in how they respond to medication, even from one menstrual cycle to the next. Inconsistencies in the bioactivity of various urinary preparations of gonadotropin may decrease the predictability of follicular response. Purified products that do not have luteinizing hormone activity may be more bioconsistent and predictable. Ultrasound examination of follicles after human chorionic gonadotropin therapy may be used to predict the number of ovulations. Gonadotropin therapy may be useful in cases of unexplained infertility, in cases where conception needs to take place before a certain time limit, and in conjunction with assisted reproductive technologies such as in vitro fertilization. Flexible doses and protocols may be needed, as not all patients experience chronic lack of ovulation.

Care and treatment, Gonadotropin, Gonadotropins, Infertility, Female, Female infertility

---

Pituitary-ovarian interactions during follicular maturation and ovulation

Article Abstract:

Hormones of the pituitary gland and the ovary may interact during the follicular phase of the menstrual cycle to promote fertility. Follicular maturation may depend on gonadotropins in the early stages, and gonadotropin therapy may accelerate follicular maturation in patients with abnormally low levels of gonadotropin. The follicle-stimulating hormone (FSH) may have a key role in promoting follicular growth. In primates, follicular growth may be promoted by FSH when luteinizing hormone (LH) is absent. High estradiol levels within follicles may not be needed to enable growth in primates. Additional LH may not be required to promote maturation of follicles in ovulation induction therapy if the body is known to produce some LH on its own. Steroids within follicles may influence the quality of oocytes. Gonadal estrogen and progesterone may enable oocyte maturation and release by interacting with the hypothalamus and pituitary gland to produce a surge of LH.

Oocytes, Oocyte donation, Estradiol, Follicle-stimulating hormone

---

Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in the human fallopian tube

Article Abstract:

Leukemia inhibitory factor (LIF) may play a role in early embryonic development and ectopic implantation. LIF is believed to enhance early embryonic cell division, differentiation, and implantation. Researchers measured amounts of messenger RNA (mRNA) for making LIF in human Fallopian tubes and cell cultures of cells from Fallopian tubes removed during ectopic pregnancy. LIF mRNA was found in greatest quantity in the inner surface of the Fallopian tube and was markedly elevated in ectopic pregnancy. LIF mRNA production was stimulated by the substances that mediate inflammation, which suggests linkages among inflammation, LIF, and ectopic pregnancy.

Measurement, Risk factors, Pregnancy, Ectopic, Ectopic pregnancy, Messenger RNA, Fallopian tubes, Pathology

Similar abstracts:

• Abstracts: Effect of three hours of hypoxia on atrial natriuretic factor gene expression in the ovine fetal heart. Characteristics and treatment of hepatic rupture caused by HELLP syndrome
• Abstracts: Cytokine-induced secretion of monocyte chemotactic protein-1 by human endometriotic cells in culture. Expression of dioxin-related transactivating factors and target genes in human eutopic endometrial and endometriotic tissues
• Abstracts: The "dangerous multipara": fact or fiction? Reduction of right atrial peak systolic velocity in growth-restricted discordant twins
• Abstracts: Endocrine and paracrine control of oocyte development. Patterns of luteinizing and follicle-stimulating hormone pulsatility in menopausal women: correlation with plasma testosterone level and vasomotor instability episodes

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.