The role of the endogenous anti-inflammatory compound gravidin in pre-eclampsia
Article Abstract:
Blood levels of the naturally occurring antiinflammatory gravidin are lower in women with preeclampsia than in women without the pregnancy complication. Preeclampsia is a complex condition characterized by high blood pressure and excessive protein secretion in the urine. Researchers tested blood samples from nine nonpregnant women, 15 women with preeclampsia, and 10 healthy pregnant women. Preeclamptic women had an average of 18 nanograms/milliliter (ng/mL) of free gravidin, while healthy pregnant women averaged 36 ng/ml and nonpregnant women had 4 ng/mL of the substance. Gravidin may reduce tissue damage by neutrophilic white blood cells in normal pregnancy.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
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The role of soluble adhesion molecules in evaluating endothelial cell activation in preeclampsia
Article Abstract:
Adhesion molecules do not appear to be responsible for the blood vessel activation that occurs in preeclampsia. Preeclampsia is a complication of pregnancy characterized by hypertension and abnormal blood clotting. Researchers measured blood levels of adhesion molecules in pregnant women with preeclampsia, healthy pregnant women and non-pregnant women. Adhesion molecules are proteins on the surface of cells that allow cells to attach to each other. Women with preeclampsia had higher levels of adhesion molecules in their blood. However, their blood samples did not activate endothelial cell cultures. Endothelium is the inner lining of blood vessels.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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Maternal neutrophil apoptosis in normal pregnancy, preeclampsia, and normotensive intrauterine growth restriction
Article Abstract:
Neutrophils of pregnant women may become resistant to natural cell death, which might lead to a complication of pregnancy called preeclampsia. Neutrophils are immune cells that are involved in inflammation. In a study of 42 women, neutrophil cell death was greatly delayed in those with preeclampsia.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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