Thrombopoietin
Article Abstract:
The discovery of thrombopoietin in 1994 raises the hope of a better treatment for thrombocytopenia. Thrombocytopenia is a drop in the number of blood platelets, which are crucial for blood clotting. Platelet transfusions are the main treatment, but they are expensive and not an ideal treatment. Thrombopoietin is a hormone that stimulates the production of blood platelets. Studies have shown that it can reverse thrombocytopenia and also raise platelet levels after chemotherapy and bone marrow transplantation.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
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Lineage-specific hematopoietic growth factors
Article Abstract:
The mechanism and clinical applications of three hematopoietic growth factors related with erythropoietin, granulocyte colony-stimulating factor, and thrombopoietin are surveyed. The clinical use of hematopoietic growth factors has improved the care of patients with inadequate blood-cell production, but these agents are costly, require parenteral administration, and could occasionally induce untoward effects.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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Do cancer cells express functional erythropoietin receptors?
Article Abstract:
The effect of erythropoietin on tumor-cell growth and survival is discussed due to the increasing concern regarding its use in patients with cancer.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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