Tracking the prevalence of transmitted antiretroviral drug- resistant HIV- 1: A decade experience
Article Abstract:
A total of 361 patients with acute or recent HIV-1 infection are prospectively studied over a decade (1995-2004) with respect to HIV-1 genotypes and longitudinal T-cell subsets and HIV-1 RNA levels to describe the changing pattern of transmitted drug-resistant HIV-1 in a well-defined cohort in New York City. Data provided have important implications for selection of empiric first- line regimens for treatment of acutely infected antiretroviral- naive individuals and reinforce the need or baseline resistance testing in acute and early HIV- 1 infection.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Bioengineering lactic acid bacteria to secrete the HIV-1 virucide cyanovirin
Article Abstract:
A study was conducted to describe the bioengineering of strains of lactic acid bacteria (LAB) to secrete the prototypic virucidal compound cyanovirin (CV-N) and demonstrate the anti-HIV-1 activity of secreted CV-N. The results suggest that recombinant LAB may serve as effective microbicidal compounds and deserve vivo testing in simian immunodeficiency virus models of mucosal virus transmission.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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Willingness to use microbicides is affected by the importance of product characteristics, use parameters, and protective properties
Article Abstract:
The Important Microbicide Characteristics (IMC) instrument is evaluated psychometrically and its relationship to willingness to use microbicides is examined. The results show that, formulation and use characteristics and product functions affect willingness to use microbicides and it continues to be addressed in product development.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
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- Abstracts: Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing. Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death
- Abstracts: Effect of antiretroviral therapy on recent trends in selected cancers among HIV-infected persons. Antidepressant treatment improves adherence to antiretroviral therapy among depressed HIV-infected patients
- Abstracts: Effect of a brief antiretroviral adherence intervention delivered by HIV care providers. Marijuana use and its association with adherence to antiretroviral therapy among HIV-infected persons with moderate to severe nausea
- Abstracts: Long-Term persistence of primary genotypic resistance after HIV-1 serconversion