Transmissible spongiform encephalopathies, amyloidoses and yeast prions: common threads?
Article Abstract:
Research presented concerns the parallels between mammalian transmissible spongiform encephalopathy, yeast proteins, and other protein-folding or aggregation diseases. Topics addressed include the role of prions in the propagation of infectious agents.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
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A novel erythroid-specific marker of transmissible spongiform encephalopathies
Article Abstract:
The pathology of transmissible spongiform encephalopathies (TSEs) are investigated in order to identify a molecular marker that may aid in the diagnosis and treatment of the disease. Results indicate that erythroid lineage cells are a common feature of TSEs, and they are detectable in accessible tissues.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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A role for complement in transmissible spongiform encephalopathies
Article Abstract:
This article examines the development of prion diseases such as spongiform encephalopathies, focusing on how the infectious agents spread from the periphery to the neurons in the brain. Research on the complement system and its role in the uptake of transmissible spongiform encephalopathy-inducing agents is discussed.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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