Unmet expectations: the brain minds
Article Abstract:
Research shows that the levels of a subunit of alpha-amino-3-hydroxy-5-methyl-4-isoxazol propionate glutamate receptors in the nucleus accumbens undergo changes during drug usage and drug withdrawal phases. Data indicate that in addition to the effect of drugs on the brain's reward circuitry, frustration of not taking it when they are anticipated can also affect the reward circuits.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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The vicious cyclin of addiction
Article Abstract:
Neurobiological research on drug addiction is presented, focusing on how addiction is associated with neural and behavioral plasticity. DNA microarray analysis is used to study how chronic cocaine exposure is linked with a cyclin-dependent kinase that changes striatal dopamine-receptor signaling.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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The cellular neurobiology of depression
Article Abstract:
Research in neurobiology finds a link between mental depression disorders and problems with the signaling pathways involved in the regulation of cell survival and neuroplasticity. Researchers suggest that drugs designed to modify molecules in the signaling pathways may be of therapeutic value.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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